TRIP PLANNING BASED ON SUBQUBO ANNEALING

Trip Planning Based on subQUBO Annealing

The trip planning problem (TPP) can be formulated as a combinatorial optimization problem that Gearbox searches for the best route to visit a series of landmarks and hotels.Meanwhile, Ising machines have attracted attention due to their efficiency in solving combinatorial optimization problems.The Ising machines solve the combinatorial optimization

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Somatic mutation profiles of MSI and MSS colorectal cancer identified by whole exome next generation sequencing and bioinformatics analysis.

BACKGROUND: Colorectal cancer (CRC) is with approximately 1 million cases the third most common cancer worldwide.Extensive research is ongoing to decipher the underlying genetic patterns with the hope to improve early cancer diagnosis and treatment.In this direction, the recent progress in next generation sequencing technologies has revolutionized

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Causal links between obesity, lipids, adipokines, and cognition: a bidirectional Mendelian-randomization analysis

BackgroundThe aim of this study was to explore the genetic level association between obesity, lipids, adipokines, and cognitive ability using bidirectional Mendelian randomization (MR) strategies.MethodsSummary data for three obesity indicators [body mass index (BMI), body fat percentage (BFP) and waist-hip ratio (WHR)], three lipid indicators [HDL

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